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. 2015 Jul 8;26(3):179–184. doi: 10.3802/jgo.2015.26.3.179

Table 2. Analysis of prognostic factors for grade ≥2 stenosis after high dose rate brachytherapy.

Variable No. Grade ≥2 actual stenosis rate at 3 years (%) p-value
Age (yr) 0.480
 <65 33 64
 ≥65 24 57
T stage 0.870
 T1 2 50
 T2 20 46
 ≥ T3 35 40
A factor (lower extension to vagina) 0.140
 T2a+T3a 6 100
 Other 51 58
N stage 0.110
 N0 39 53
 N1 18 74
Total prescribed dose (EQD2: α/β=3) 0.970
 <84 Gy 24 52
 ≥ 84 Gy 33 66
External beam RT dose (EQD2: α/β=3) 0.660
 <30 Gy 48 61
 ≥ 30 Gy 9 49 (at 2 yr)
Brachytherapy dose (EQD2: α/β=3) 0.550
 <63 Gy 33 48
 ≥ 63 Gy 24 81
Modality 0.180
 Intracavitary 42 72
 Interstitial 15 39
Chemotherapy 0.450
 Received 27 56
 Not received 30 61
Pallor reaction at 6 months 0.001
 <Grade 2 47 53
 ≥ Grade 2 10 100

EQD2, the biologically equivalent dose calculated into equivalent 2-Gy fractions; N, node; RT, radiotherapy; T, tumor.