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. 2015 Jul 22;5:12442. doi: 10.1038/srep12442

Figure 1. Enhancement of HIV-1 infection of latent astrocytes by bryostatin stimulation.

Figure 1

(a) NHA and (c) U-87 cells were infected with HIV-1NL4.3 (100 ng p24/106), and supernatants were collected at 3, 6, and 8 dpi. After collection, the cells were treated with bryostatin (100 ng/ml), and supernatants were collected 2 and 5 days later. The release of viral p24 into culture supernatants was monitored by ELISA. The fold induction of treated over infected cells 2 days after treatment is shown. The mean values (mean ± S.D.) of three independent experiments are shown. (b) The d10/d8 dpi ratio of NHA cells. (d) The d10/d8 dpi ratio of U-87 cells. The results of three independent experiments expressed as the fold increase relative to infected cells.