Table 1. Comparison of potassium current density and relative amplitude in ventricular myocyte.
Ito | IKslow1 | IKslow2 | Isus | ||
---|---|---|---|---|---|
ENDO | |||||
WT | Density (pA/pF) | 11.80±0.82 | 8.78±1.51 | 7.71±0.52 | 4.67±0.34 |
n = 20 | Amplitude (%) | 36±0.31 | 27±0.62 | 24±0.54 | 13±0.29 |
Kv4.2-/- | Density (pA/pF) | 6.89±0.44* | 9.23±0.91 | 7.25±0.51 | 4.02±0.55 |
n = 21 | Amplitude (%) | 24±0.27 | 33±0.42 | 26±0.37 | 17±0.41 |
EPI | |||||
WT | Density (pA/pF) | 28.37±1.21* | 33.45±2.95* | 18.52±1.77* | 7.33±0.57* |
n = 14 | Amplitude (%) | 32±0.86 | 38±0.40 | 21±0.96 | 9±0.37 |
Kv4.2-/- | Density (pA/pF) | 8.96±0.78^ # | 31.12±1.88^ # | 10.98±0.63^ # | 4.39±0.28^ |
n = 54 | Amplitude (%) | 17±0.51 | 56±0.45 | 20±0.84 | 7±0.23 |
* P<0.05, compared to WT ENDO
^ P<0.05, compared to WT EPI
# P<0.05, compared to Kv4.2-/- ENDO