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. 2015 Jun 2;3(6):e12415. doi: 10.14814/phy2.12415

Figure 6.

Figure 6

Aerobic training induces angiogenesis in adipose tissue of IS, but not IR subjects. (A) Representative photomicrograph of lectin staining for vessels in adipose tissue. (B) Poor aerobic fitness is associated with larger adipocytes, as adipocyte size and VO2max are inversely correlated (P < 0.05, r = −0.47, N = 24). (C) Following training, vessels per adipocyte is increased in IS, but not IR participants; there was a significant interaction between training and insulin resistance (training × IR P < 0.01), a significant increase in vessels within IS subjects (IS pre versus IS post P = 0.05 post hoc), and a significant difference between IS and IR adipose vessels following training (IS post versus IR post P < 0.05 post hoc). RMANOVA, N = 10 IS, N = 14 IR. (D) CD31 gene expression was not significantly affected by training or insulin resistance (NS for all covariates). (E) TIE1 gene expression tended to be lower in IR versus IS, regardless of training (IS versus IR P = 0.05). RMANOVA, N = 6 IS, N = 8 IR.