Table 2.
P15 | |||||||||
---|---|---|---|---|---|---|---|---|---|
CHOW | PF | ETOH | CHOW | PF | ETOH | CHOW | PF | ETOH | |
M/F (n) | 4/3 | 6/1 | 4/2 | 5/2 | 4/5 | 2/4 | 4/3 | 3/4 | 3/5 |
wt, g | 33.5 ± 0.8 | 35.0 ± 0.6 | 32.9 ± 0.8* | ||||||
aCSF | NIP | Gabazine | |||||||
fH, bpm | 408 ± 18 | 419 ± 11 | 440 ± 17 | 436 ± 18 | 432 ± 10 | 439 ± 16 | 440 ± 14 | 394 ± 17 | 442 ± 15 |
fR, breaths/min | 118 ± 9 | 114 ± 6 | 124 ± 3 | 143 ± 8# | 132 ± 5 | 132 ± 5 | 119 ± 10 | 124 ± 9 | 119 ± 3 |
TB, °C | 33.1 ± 0.3 | 33.1 ± 0.4 | 33.0 ± 0.6 | 34.1 ± 0.4 | 33.4 ± 0.3 | 33.9 ± 0.4 | 33.9 ± 0.2 | 33.6 ± 0.7 | 34.4 ± 0.4 |
CONTROL | CONTROL | CONTROL | |||||||
wt, g | 34.3 ± 0.5 | ||||||||
fH, bpm | 414 ± 10 | 434 ± 9 | 417 ± 12 | ||||||
fR, breaths/min | 116 ± 5$$ | 137 ± 4 | 121 ± 6 | ||||||
TB, °C | 33.1 ± 0.3 | 33.7 ± 0.2 | 33.8 ± 0.4 |
P21 | |||||||||
---|---|---|---|---|---|---|---|---|---|
CHOW | PF | ETOH | CHOW | PF | ETOH | CHOW | PF | ETOH | |
M/F (n) | 3/3 | 2/4 | 2/5 | 5/1 | 2/4 | 3/3 | 4/3 | 2/3 | 3/3 |
wt, g | 52.2 ± 1.2* | 57.5 ± 2.1 | 52.0 ± 1.2* | ||||||
aCSF | NIP | Gabazine | |||||||
fH, bpm | 428 ± 21 | 421 ± 17 | 445 ± 17 | 419 ± 17 | 432 ± 25 | 436 ± 14 | 463 ± 7 | 480 ± 10 | 459 ± 11 |
fR, breaths/min | 115 ± 9 | 123 ± 6 | 121 ± 4 | 140 ± 12 | 135 ± 6 | 118 ± 7$ | 147 ± 11## | 131 ± 6.8 | 127 ± 5.6 |
TB, °C | 33.7 ± 0.8 | 33.4 ± 2.0 | 35.3 ± 0.5 | 34.0 ± 0.7* | 31.1 ± 2.3 | 34.8 ± 0.5$, ** | 33.7 ± 0.7 | 33.5 ± 0.4 | 34.5 ± 0.5 |
CONTROL | CONTROL | CONTROL | |||||||
wt, g | 54.7 ± 1.2 | ||||||||
fH, bpm | 425 ± 13 | 425 ± 14 | 470 ± 6&,$ | ||||||
fR, breaths/min | 118 ± 5 | 138 ± 7 | 141 ± 7& | ||||||
TB, °C | 33.6 ± 1.0 | 32.5 ± 1.2 | 33.7 ± 0.4 |
The weight (wt) was measured at P15 and P21 for all CHOW, PF, ETOH and CONTROL pups independent of injections: * different from PF (P < 0.05). All three diets and the CONTROL group are compared for fH, fR and TB:
different from PF NIP (*P < 0.05, **P < 0.01)
different from CHOW aCSF (#P < 0.05, ##P < 0.01);
different from CONTROL NIP ($P < 0.05, $$P < 0.01) and
different from CONTROL aCSF (&P < 0.05).
M/F, male/female
wt, weight
fH, heart rate
fR, respiratory rate
TB, body temperature.
All values are mean (SEM).