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. 2015 Jun 9;3(6):e12424. doi: 10.14814/phy2.12424

Table 2.

Baseline data obtained before the first trial of the pharmacology study.

P15
CHOW PF ETOH CHOW PF ETOH CHOW PF ETOH
M/F (n) 4/3 6/1 4/2 5/2 4/5 2/4 4/3 3/4 3/5
wt, g 33.5 ± 0.8 35.0 ± 0.6 32.9 ± 0.8*
aCSF NIP Gabazine
fH, bpm 408 ± 18 419 ± 11 440 ± 17 436 ± 18 432 ± 10 439 ± 16 440 ± 14 394 ± 17 442 ± 15
fR, breaths/min 118 ± 9 114 ± 6 124 ± 3 143 ± 8# 132 ± 5 132 ± 5 119 ± 10 124 ± 9 119 ± 3
TB, °C 33.1 ± 0.3 33.1 ± 0.4 33.0 ± 0.6 34.1 ± 0.4 33.4 ± 0.3 33.9 ± 0.4 33.9 ± 0.2 33.6 ± 0.7 34.4 ± 0.4
CONTROL CONTROL CONTROL
wt, g 34.3 ± 0.5
fH, bpm 414 ± 10 434 ± 9 417 ± 12
fR, breaths/min 116 ± 5$$ 137 ± 4 121 ± 6
TB, °C 33.1 ± 0.3 33.7 ± 0.2 33.8 ± 0.4
P21
CHOW PF ETOH CHOW PF ETOH CHOW PF ETOH
M/F (n) 3/3 2/4 2/5 5/1 2/4 3/3 4/3 2/3 3/3
wt, g 52.2 ± 1.2* 57.5 ± 2.1 52.0 ± 1.2*
aCSF NIP Gabazine
fH, bpm 428 ± 21 421 ± 17 445 ± 17 419 ± 17 432 ± 25 436 ± 14 463 ± 7 480 ± 10 459 ± 11
fR, breaths/min 115 ± 9 123 ± 6 121 ± 4 140 ± 12 135 ± 6 118 ± 7$ 147 ± 11## 131 ± 6.8 127 ± 5.6
TB, °C 33.7 ± 0.8 33.4 ± 2.0 35.3 ± 0.5 34.0 ± 0.7* 31.1 ± 2.3 34.8 ± 0.5$, ** 33.7 ± 0.7 33.5 ± 0.4 34.5 ± 0.5
CONTROL CONTROL CONTROL
wt, g 54.7 ± 1.2
fH, bpm 425 ± 13 425 ± 14 470 ± 6&,$
fR, breaths/min 118 ± 5 138 ± 7 141 ± 7&
TB, °C 33.6 ± 1.0 32.5 ± 1.2 33.7 ± 0.4

The weight (wt) was measured at P15 and P21 for all CHOW, PF, ETOH and CONTROL pups independent of injections: * different from PF (P < 0.05). All three diets and the CONTROL group are compared for fH, fR and TB:

*

different from PF NIP (*P < 0.05, **P < 0.01)

#

different from CHOW aCSF (#P < 0.05, ##P < 0.01);

$

different from CONTROL NIP ($P < 0.05, $$P < 0.01) and

&

different from CONTROL aCSF (&P < 0.05).

M/F, male/female

wt, weight

fH, heart rate

fR, respiratory rate

TB, body temperature.

All values are mean (SEM).