Table 2.

Myocardial cytochrome P450 metabolites

	WT (n = 7)			sEH-KO (n = 6)
	EET	DHET	EET/DHET	EET	DHET	EET/DHET
14,15-	1.413 ± 0.324	0.063 ± 0.021	54.4 ± 27.3	2.438 ± 0.279†	0.022 ± 0.007†	149.915 ± 29.22†
11,12-	1.736 ± 0.351	0.049 ± 0.024	180.82 ± 80.00	4.034 ± 0.603†	0.034 ± 0.018†	255.341 ± 59.6†
8,9-	2.226 ± 0.379	0.113 ± 0.012	20.695 ± 3.031	5.379 ± 1.503†	0.135 ± 0.024	56.294 ± 23.055
5,6-	2.414 ± 0.480	0.229 ± 0.071	18.565 ± 7.919	4.300 ± 0.611	0.457 ± 0.117	14.042 ± 5.007

EETs and DHETs are quantified as picogram per milligram of tissue.

^†Significant difference compared to corresponding value in WT mice.