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. 2015 Jul 22;7:140. doi: 10.3389/fnagi.2015.00140

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Copyright © 2015 Biressi and Gopinath.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution and reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Overview of the signaling pathways in satellite cells (SCs) during atrophy. Schematic representation of the major signaling pathways implicated in SC biology under different atrophic stimuli (see text for details). Cross-talks between different pathways are highlighted by positive and negative regulation at different levels. Abbreviations: AR, androgen receptor; GR, glucocorticoid receptor; Il-6R, Interleukin-6 receptor; IGF-1R, IGF-1 receptor; LIFR, LIF receptor; AT1R, Angiotensin II receptor 1; ActRII, Activin receptor 2; Fst, Follistatin; Mst, Myostatin; NICD, Notch intracellular domain; MT, mitochondria.