Table 1.
Condition | Changes in number | Changes in function | Notes | References |
---|---|---|---|---|
Aging | ↓ = | Yes | ↓ proliferation ↓ myogenic differentiation |
Snijders et al. (2009) and Alway et al. (2014) |
Cachexia | ↑ | Yes | ↑ activation/proliferation ↓ differentiation/fusion |
Penna et al. (2010) and He et al. (2013) |
Denervation | ↑* | Yes | ↑ activation/proliferation ↓ fusion |
Viguie et al. (1997), Borisov et al. (2005) and Doppler et al. (2008) |
Hind limb suspension | ↓ = ↑ | Yes | ↓ proliferation ↓ differentiation |
Mitchell and Pavlath (2004) Brooks and Myburgh (2014) |
Glucocorticoids | n.d. | Yes | ↓ proliferation ↓ differentiation |
Dong et al. (2013) |
DMD | ↑ | Yes | ↓ proliferation ↓ myogenic differentiation/fusion |
Blau et al. (1983) and Delaporte et al. (1984) Jasmin et al. (1984), Melone et al. (1999) and Biressi et al. (2014) |
↑, Increase; ↓, decrease; =, unchanged; n.d., not defined; * initial increase, but reduced in the long-term (Viguie et al., 1997).