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. 2015 Jul 22;7:140. doi: 10.3389/fnagi.2015.00140

Table 1.

Satellite cell alterations in different atrophic conditions.

Condition Changes in number Changes in function Notes References
Aging ↓ = Yes ↓ proliferation
↓ myogenic differentiation
Snijders et al. (2009) and Alway et al. (2014)
Cachexia Yes ↑ activation/proliferation
↓ differentiation/fusion
Penna et al. (2010) and He et al. (2013)
Denervation ↑* Yes ↑ activation/proliferation
↓ fusion
Viguie et al. (1997), Borisov et al. (2005) and Doppler et al. (2008)
Hind limb suspension ↓ = ↑ Yes ↓ proliferation
↓ differentiation
Mitchell and Pavlath (2004)
Brooks and Myburgh (2014)
Glucocorticoids n.d. Yes ↓ proliferation
↓ differentiation
Dong et al. (2013)
DMD Yes ↓ proliferation
↓ myogenic differentiation/fusion
Blau et al. (1983) and Delaporte et al. (1984)
Jasmin et al. (1984), Melone et al. (1999) and Biressi et al. (2014)

↑, Increase; ↓, decrease; =, unchanged; n.d., not defined; * initial increase, but reduced in the long-term (Viguie et al., 1997).