Fig. 2.
Histological analysis shows abnormality in the labyrinthine zone in ΔmiR-127 and ΔRtl1. (A,B) Histological analysis of WT littermate and ΔmiR-127 or ΔRtl1, respectively. H&E-stained paraffin sections of E18.5 placentae. Dashed lines demarcate Lz (bottom layer), Jz (middle layer) and Db (top layer). Scale bars: 500 μm. (C-F) The volumes of placental and labyrinthine compartments in WT, ΔmiR-127 and ΔRtl1. Lz, labyrinthine zone; Jz, junctional zone; Db, decidual basalis; Ch, chorion; MBS, maternal blood spaces; FC, fetal capillaries; LT, labyrinthine trophoblast. *P<0.05, **P<0.01, ***P<0.005 (Student's t-test). Error bars indicate s.d.