Table 1.
Cell line origin, doubling times and IC50 values of all thyroid carcinoma cell lines examined after 48 h of GX15-070 treatment (MTT assay), mean of three independent experiments
| Cell line | Origin | IC50 GX15070 (μM) | Doubling time (h) |
|---|---|---|---|
| FTC133 | FTC | 0.052 | 42 |
| FTC236 | FTC | 0.089 | 37 |
| FTC238 | FTC | 0.048 | 30 |
| ML1 | FTC | 0.16 | 68 |
| TT2609 | FTC | 0.62 | 52 |
| RO82W | FTC | 1.12 | 48 |
| BHT101 | PTC | 0.072 | 46 |
| B-CPAP | PTC | 0.15 | 36 |
| TPC-1 | PTC | 0.21 | 30 |
| K1 | PTC | 3.25 | 38 |
| SW1736 | ATC | 0.11 | 37 |
| C643 | ATC | 0.049 | 31 |
| HTh7 | ATC | 0.078 | 36 |
| HTh74 | ATC | 0.21 | 43 |
| HTh83 | ATC | 0.23 | 32 |
| 8305 | ATC | 2.16 | 30 |
| 8505 | ATC | 0.16 | 37 |