Table 3.
Mean fold changes in the expression of tested genes in blood cells after X-irradiation
| Mean fold change | ||||||||
|---|---|---|---|---|---|---|---|---|
| 0.6 Gy | 2 Gy | |||||||
| 6 h | 12 h | 24 h | 48 h | 6 h | 12 h | 24 h | 48 h | |
| SERPINE1 | 0.57 | 0.77 | 0.75 | 0.88 | 1.01 | 0.71 | 0.96 | 0.75 |
| TNFRSF10B | 1.71 | 2.45 | 2.29 | 1.85 | 3.58 | 3.48 | 2.89 | 1.98 |
| VWCE | 0.65 | 1.22 | 1.11 | 1.49 | 0.94 | 1.30 | 1.40 | 2.04 |
| GADD45A | 2.61 | 2.59 | 3.49 | 3.20 | 3.98 | 4.28 | 6.61 | 5.91 |
| CDKN1A | 3.49 | 2.83 | 1.76 | 3.61 | 6.40 | 5.33 | 3.41 | 8.13 |
| MDM2 | 1.60 | 1.89 | 1.81 | 1.67 | 1.69 | 2.22 | 2.20 | 2.11 |
| BBC3 | 5.45 | 5.92 | 6.00 | 3.77 | 8.57 | 8.14 | 8.77 | 5.27 |
| SESN2 | 1.42 | 1.59 | 1.48 | 1.17 | 1.75 | 1.74 | 1.69 | 1.45 |
| BAX | 3.37 | 4.11 | 4.56 | 3.78 | 3.74 | 5.02 | 4.96 | 4.98 |
| DDB2 | 5.97 | 5.67 | 5.22 | 4.56 | 7.99 | 8.62 | 7.50 | 6.05 |
| ATF3 | 1.85 | 1.13 | 1.39 | 1.51 | 3.17 | 1.99 | 1.48 | 1.19 |
| PLK3 | 1.52 | 1.76 | 1.33 | 1.59 | 2.00 | 2.33 | 1.80 | 2.41 |
| GDF15 | 3.62 | 2.68 | 1.41 | 2.07 | 12.40 | 7.21 | 2.82 | 4.81 |
| BCL2 | 1.14 | 1.16 | 1.02 | 0.88 | 1.48 | 1.20 | 0.98 | 0.82 |
| TNFSF4 | 4.22 | 5.08 | 3.45 | 3.89 | 12.49 | 13.44 | 10.03 | 8.09 |
| FDXR | 20.71 | 16.37 | 10.60 | 8.95 | 34.16 | 29.43 | 24.05 | 18.64 |
Genes for which at least twofold changes in expression were observed for all time points for at least one dose are given in bold