Fig. 2.

Lf intervention upregulates the neurotrophin-signaling pathway in postnatal piglets. The activated genes are denoted with a red star: p < 0.05~0.001. Genes increased by Lf intervention vs. the control group of piglets are summarized in Table 2. A number of functional studies have shown that this signaling cascade network can affect neural development, neuronal structure construction, and long-term potentiation, as described in the text. The Lf-induced increased in BDNF expression was confirmed by qPCR, as shown in Fig. 3