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. Author manuscript; available in PMC: 2015 Jul 22.
Published in final edited form as: Compr Physiol. 2015 Jul 1;5(3):1265–1280. doi: 10.1002/cphy.c140074

Figure 3.

Figure 3

Examples of adhesive interactions between platelets (red) and leukocytes (blue). Platelets contain a number of integrins and cell adhesion molecules on their surface which bind to both leukocytes and endothelial cells (green). Major cell adhesion molecule interactions include (platelet-leukocyte) P-selectin-PSGL-1 and GP1bα-Mac-1. Platelets also adhere to endothelial cells and help capture flowing leukocytes from the circulation. Reprinted from reference (85) with permission from Wiley.