TABLE 3.
Genes induced by Sox17β only
| Name |
Accession number |
Unigene cluster |
Domains/ homology/ description |
Fold Change by Mixer |
Fold Change by Sox17β |
|---|---|---|---|---|---|
| ElrD | u17599 | Xl.1036 | RNA-binding protein HuD | 1.0, 1.0 | 2.6, 10.1 |
| Clast3 | CB561662 | Xl.10510 | CD40 ligand-activated specific transcript 3 | 1.2, −1.0 | 2.6, 3.0 |
| Otx2*† | AW199379 | Xl.3004 | Orthodenticle-A like homeobox protein | 1.7, 1.2 | 6.2, 8.1 |
| 1.2, 1.1 | 2.9, 5.2 | ||||
| Irx4 † | AF338157 | Xl.12086 | Iroquois-4 homeobox transcription factor | 1.3, 1.1 | 14.5, 18.6 |
| Nr2f2 | BC044975 | Xl.14532 | Nuclear receptor subfamily 2, group F, member 2 | −1.0, 1.0 | 2.0, 2.8 |
| FoxC1 | AF116844 | Xl.180 | Winged helix transcription factor (Xfd-11) | 1.8, 1.2 | 2.5, 4.1 |
| Pdgf | BC043948 | Xl.20029 | Platelet derived growth factor receptor alpha | 1.2, 1.4 | 2.4, 2.3 |
| Crgb † | AF071563 | Xl.21441 | Crystallin, gamma B | 1.1, 1.1 | 10.1, 21.2 |
| Eomes | U75996 | Xl.373 | T-domain gene Eomesodermin | 1.5, 1.1 | 2.8, 3.0 |
| Ash1 † | M98272 | Xl.450 | Achaete-scute protein homologue | 1.3, 1.6 | 5.4, 14.3 |
| Xgam | M63446 | Xl.5871 | Gamma-tubulin | 1.3, 1.6 | 2.1, 2.9 |
| Foxd1-A | AJ011652 | Xl.66 | Forkhead box D1 (brain factor 2, Xbf-2) | 1.3, 1.2 | 2.6, 4.1 |
| Gsc*† | BJ056432 | Xl.801 | Goosecoid homeobox protein | 1.1, −1.1 | 5.0, 4.1 |
| 2.5, 1.3 | 16.3, 17.5 | ||||
| Gpr-4 | AY553187 | Xl.45565 | G-protein coupled receptor 4 | 1.3, 2.2 | 2.6, 4.3 |
| Xlim-1 | CB562197 | Xl.32655 | LIM domain-containing homeobox protein | 1.2, 1.1 | 2.4, 2.5 |
| Xtwi | M27730 | Xl.879 | bHLH Twist homolog 1 | 2.2, −1.1 | 9.3, 17.7 |
| EST-22 † | BG810694 | Xl.2565 | similar to alpha-Tubulin at 84B | −1.1, 1.0 | 84.2, 106.2 |
| EST-23 | BI478249 | Xl.19057 | similar to human amino acid transporter | −1.1, −1.1 | 2.8, 5.7 |
| EST-24 | BM191866 | Xl.7085 | similar to human hypothetical protein FLJ20511 | 1.1, 1.2 | 2.0, 2.3 |
| EST-25 | BJ044317 | Xl.1419 | similar to human Interferon regulatory factor 1 | −1.0, 1.1 | 8.0, 2.3 |
| EST-26 | BC041234 | Xl.16040 | similar to human Phosphatidylserine decarboxylase | 1.2, 1.5 | 2.0, 3.0 |
| EST-27* | BG021407 | Xl.34405 | similar to human new Ets-related factor | 1.4, 1.1 | 2.3, 3.8 |
| 1.1, 1.1 | 2.9, 4.9 | ||||
| EST-28 | BJ043709 | Xl.8559 | similar to human Protocadherin 10, isoform 1 precursor |
1.1, 1.4 | 4.6, 9.2 |
| EST-29 | CA792418 | Xl.1295 | similar to human HRAS1-related cluster protein 1 | −1.1, −1.0 | 3.7, 5.1 |
| EST-30 | BJ054524 | Xl.16561 | similar to human Chloride channel protein CLC-KA | −1.1, −1.0 | 2.9, 16.0 |
| EST-31 | BM172631 | Xl.16695 | similar to human Elongation of very long chain fatty acids |
1.3, −1.0 | 3.5, 4.4 |
| EST-32 | BI348356 | Xl.18627 | similar to human hypothetical protein DKFZp586N041.1 |
1.4, 1.5 | 2.1, 2.1 |
| EST-33 | BQ385449 | Xl.19414 | similar to human Rsu-1 homolog | 1.1, 1.1 | 2.8, 3.7 |
| EST-34 † | BJ044473 | Xl.15931 | similar to mouse Doublesex- and mab-3-related txn factor |
1.3, 1.1 | 6.3, 6.3 |
| EST-35 † | BJ048106 | Xl.23586 | likely paralog of Xtwik2 | 1.3, 1.7 | 8.5, 11.4 |
| EST-36 | BJ085642 | Xl.13426 | similar to human C2orf17 unnamed protein | 1.3, 1.1 | 2.4, 2.2 |
| EST-37 | BJ079356 | Xl.14106 | frog gene | 1.4, 2.3 | 2.7, 2.6 |
| EST-38 | BG023545 | Xl.2439 | frog gene | 1.3, 2.0 | 2.5, 5.2 |
*
Indicates transcripts represented more than once on the array and meet the required standards twice in our data set for experiments 1 and 2.
†
Represents transcripts whose induction by Sox17β was greater than 5.0 for experiments 1 and 2.