Table 2.
Mean Arterial Pressure (MAP), Serum creatinine (SCr), SUN and Cystatin C in NC, CY, WT and HT male mice.
| Parameters | MAP (mmHg, Mean ± SD) | SCr [mg/dL; Median [Lower Quartile to Upper Quartile]) | SUN (mg/dL, Mean ± SD) | Cystatin C (mg/L, Mean ± SD) |
|---|---|---|---|---|
| NC - 5 weeks | 118.81 ± 9.07 (n = 6) | 0.46 (0.36 to 0.55) (n = 6) | 27.88 ± 1.33 (n = 6) | – – |
|
| ||||
| CY - 5 weeks | 129.47 ± 6.78*, aaa, b (n = 6) | 0.44 (0.30 to 0.56)b (n = 6) | 29.23 ± 3.21 (n = 6) | – – |
|
| ||||
| NC - 10–13 weeks | 0.37 (0.35 to 0.38) (n = 9) | 25.23 ± 1.22 (n = 9) | ||
| NC - 13 weeks | 132.86 ± 4.21 (n = 6) | 3.21 ± 0.50 (n = 6) | ||
| CY - 10–13 weeks | 0.32 (0.30 to 0.35) ** (n = 9) | 26.70 ± 1.43* (n = 9) | ||
| CY - 13 weeks | 149.79 ± 4.66***, b (n = 6) | 3.61 ± 0.53 (n = 7) | ||
| NC - 24 weeks | 131.64 ± 13.08 (n = 6) | 0.23 (0.21 to 0.34) (n = 6) | 27.80 ± 4.62 (n = 6) | – – |
|
| ||||
| CY - 24 weeks | 139.95 ± 7.20 (n = 6) | 0.33 (0.22 to 0.37) (n = 7) | 30.14 ± 5.10 (n = 7) | – – |
|
| ||||
| WT - 10–13 weeks | 0.38 (0.36 to 0.39) (n = 8) | 26.27 ± 1.16 (n = 8) | – – | |
| WT - 13 weeks | 127.54 ± 2.99 (n = 8) | |||
|
| ||||
| HT - 10–13 weeks | 0.36 (0.34 to 0.36) (n = 8) | 25.34 ± 1.18 (n = 8) | – – | |
| HT - 13 weeks | 131.03 ± 4.36 (n = 6) | |||
MAP, SUN and cystatin C were compared using the nonpaired t test.
SCr was compared using the Mann-Whitney test.
Group-time analyses was performed using ANOVA or Kruskal Wallis.
*
p < 0.05 versus NC.
**
p < 0.01 versus NC.
***
p < 0.01 versus NC.
aaa
p < 0.001 versus 13 weeks.
b
p < 0.05 versus 24 weeks.