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. 2015 Jul 22;6:147. doi: 10.3389/fphar.2015.00147

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Copyright © 2015 Abu-Sanad, Wang, Hasheminasab, Panasci, Noë, Rosca, Davidson, Amrein, Sharif-Askari, Aloyz and Panasci.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Cell cycle analysis of (A) HCT-116, (B) HT-29, and (C) LoVo cell lines 24 h post treatment with IC₅₀ concentrations of SN38 (S) and/or 0.5 μM ABT-888 (A) 1 μM VE-821 (V) or both (AV). (NT) cells treated with vehicle alone, (AV) ABT-888 and VE-821, (SA) SN38 and ABT-888, (SV) SN38 and VE-821, and (SAV) SN38, ABT-888 and VE-821 in combination.