Fig 6. PA-dPEG24 inhibits complement activation in rat serum, mouse plasma and non-human primate serum.

Hemolytic assays using (A) Wistar rat serum, (B) mouse plasma and (C) cynomolgus monkey serum were performed with increasing amounts PA-dPEG24 dissolved in 100mM Na₂HPO₄ with 0.9% NaCl buffer for rat serum, 10mM Na₂HPO₄ with 0.9% NaCl for cynomolgus monkey serum and 0.9% NaCl for mouse plasma. Serum or plasma were incubated with peptide and then added to human AB erythrocytes. Values are the means of three independent experiments. Error bars represent the SEM.