Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2015 Jul 20;15:e30.

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

Copyright © 2015 The Author(s)

This is an open-access article whereby the authors retain copyright of the work. The article is distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

PMC Copyright notice

Human mesenchymal stem cells (top) and human dermal fibroblasts (bottom) express lower levels of myofibroblast markers when cultured with PermeaDerm derivatives than with Biobrane. Human mesenchymal stem cells were cultured on membranes for 7 days in the presence of 10% fetal bovine serum before total RNA was extracted and analyzed by quantitative real-time PCR for expression of the myofibroblast markers, αSMA, and fibronectin. PermeaDerm and its derivatives reduced expression of myofibroblast markers compared with cell grown with Biobrane. Addition of antiscar compound (AS) to PermeaDerm derivatives decreased myofibroblast marker production. Data were analyzed by analysis of variance using Prism software from Graphpad (*P < .05, **P < .01). αSMA indicates α-smooth muscle actin.