Correlations of hypothalamic gene expression, serum hormones, and physiological parameters. A, mPOA turquoise module eigenvalues positively correlated to serum P4. B–G, Significant correlations between individual mPOA gene expression and hormones are shown. Serum P4 correlated with Oxtr, Lepr, Pomc, Ghrh, and Npy (B–F), which all belonged to the mPOA turquoise module. G, Gene expression of Ghrh (mPOA) positively correlated with serum Cort. H–J, Correlations between physiological parameters and hormones. Correlations between pituitary index and GH (H), pituitary index and TSH (I), and adrenal index and E2 (J) were significant when tested with E2 and covariate interaction. Correlations between uterine diameter and E2 (K), adrenal index and pituitary index (L), and adrenal index and body weight (M) were significant when tested without E2 and covariates interaction. A statistical summary is provided in Supplemental Table 3.