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. 2015 Apr 28;29(8):3426–3435. doi: 10.1096/fj.15-271056

TABLE 3.

Statistical tests for evidence of negative selection at 3 CD SNPs, according to cross-cohort comparison method 1

Comparison Null hypothesis tested SNPs tested (n) Unadjusted P Variance-adjusted P
GAM vs. EUR CD SNP MAFs are not significantly reduced in GAM compared with EUR 174 0.004 0.007
GAM vs. MKK CD SNP MAFs are not significantly reduced in GAM compared with MKK 149 0.002 0.002
MKK vs. EUR CD SNP MAFs are not significantly reduced in MKK compared with EUR 141 0.03 0.04