Fig. 4.

Odds ratio of incremental cut-off values for serum creatinine increase and mortality in the entire cohort. A 0.3 mg/dl increase in serum creatinine is the lowest robust cut-off value associated with 3 months mortality (a), but only if this increase is based on ΔADM > 0.3 mg/dl (OR 2.42(1.06-5.54). At year 1 (b) and year 2 (c), a serum creatinine increase of 0.3 mg/dl is also the lowest robust cut-off value associated with mortality but again only if this increase is based on ΔADM > 0.3 mg/dl (RR 2.11(1.24-3.6) and RR 1.79(1.06-3.03) at year 1 and year 2 respectively)