Table 1.
Demographics in AKI vs no-AKI according to different definitions
| AKI definition | ΔADM > 0.3 | ΔHIS > 0.3 | ΔEST > 0.3 | ||||||
|---|---|---|---|---|---|---|---|---|---|
| AKI/noAKI (n/%) | AKI (27/13.8) | no AKI (166/85.1) | p value | AKI(98/50.3) | no AKI (97/49.7) | p value | AKI (89/45.6) | no AKI (106/54.4) | p value |
| %male | 66.7 | 61.4 | 0.6 | 67.3 | 57.7 | 0.17 | 65.2 | 60.4 | 0.49 |
| Age(y)(mean/sd) | 66.2(10.7) | 60.7(15.6) | 0.08 | 62.6(14.1) | 60.2(15.8) | 0.28 | 65.1(13.5) | 58.2(15.5) | 0.001 |
| APACHE II | 27(9) | 22(9) | 0.003 | 25(8) | 19(9) | <0.001 | 25(8) | 20(9) | <0.001 |
| Ventilation(n/%) | 25/92.6 | 80/48.2 | <0.001 | 59/60.2 | 47/48.5 | 0.10 | 55/61.8 | 51/48.1 | 0.06 |
| CKD(n/%) | 7/25.9 | 23/13.9 | 0.11 | 18/18.4 | 12/12.4 | 0.25 | 25/28.1 | 5/4.7 | <0.001 |
| ICU admission serum creatinine (mg/dl) | 1.29(0.66) | 1.05(0.89) | 0.01 | 1.67(1.25) | 0.79(0.40) | <0.001 | 1.76(1.24) | 0.80(0.39) | <0.001 |
| Historical baseline creatinine (mg/dl) | 0.98(0.41) | 0.83(0.32) | 0.18 | 0.88(0.37) | 0.82(0.34) | 0.52 | 0.98(0.35) | 0.79(0.32) | 0.001 |
| RRT need(n/%) | 14/51.9 | 13/7.8 | <0.001 | 23/23.5 | 4/4.1 | <0.001 | 24/27 | 3/2.8 | <0.001 |
| ICU LOS(d) in ICU survivors | 15(22) | 6(8) | 0.009 | 6(9) | 5(10) | 0.34 | 7(9) | 6(9) | 0.24 |
| ICU Mort(n/%) | 12/44.4 | 31/18.7 | 0.003 | 25/25.5 | 20/20.6 | 0.42 | 22/24.7 | 23/21.7 | 0.62 |
| Mort at three months(n/%) | 13/48.1 | 46/27.7 | 0.03 | 32/32.7 | 29/39.9 | 0.68 | 30/33.7 | 31/29.2 | 0.50 |
| Mort at 1 year(n/%) | 17/63 | 66/39.8 | 0.024 | 42/42.9 | 43/44.3 | 0.84 | 41/46.1 | 44/41.5 | 0.52 |
| Mort at 2 years(n/%) | 17/63 | 79/47.6 | 0.14 | 47/48 | 51/52.6 | 0.52 | 46/48.3 | 51/51.9 | 0.62 |
AKI Acute kidney injury, ΔADM > 0.3 = Serum creatinine increase > 0.3 mg/dl based on the difference between the value 24 h after admission and ICU admission, ΔHIS > 0.3 = Serum creatinine increase > 0.3 mg/dl based on the difference between the highest value during the first 24 h after ICU admission and a historical baseline value, ΔEST > 0.3 = Serum creatinine increase > 0.3 mg/dl based on the difference between the highest value during the first 24 h after ICU admission and an estimated baseline value, APACHE II Acute physiology and chronic health evaluation II score, CKD Chronic kidney disease, RRT Renal replacement therapy, ICU LOS Intensive care unit length of stay, Mort Mortality