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. 2015 Jan 14;6(4):436–442. doi: 10.1111/jdi.12314

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© 2014 The Authors. Journal of Diabetes Investigation published by Asian Association of the Study of Diabetes (AASD) and Wiley Publishing Asia Pty Ltd

This is an open access article under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made.

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An overview of the protocol of the present study. Evaluations made when bolus insulin was reduced by 9 units/day and an added-on therapy of concomitant liraglutide used were established as evaluation-1. Evaluations made 16 weeks after the start of this concomitant therapy were established as evaluation-2. We measured the blood glucose levels before and after dinner during the 28 days immediately before each evaluation, and set their mean value and SD levels as the individual patient's blood glucose level before and after dinner, and SD level before and after the change in treatment. We evaluated the changes in these blood glucose levels before and after dinner, and the SD values of the 20 target patients. We also measured the blood glucose levels before and after three meals in an optional day within 1 week immediately before each evaluation, and evaluated the changes in various blood glucose levels between before and after the change in therapy. SMBG, self-monitoring blood glucose.