Table 2.
Association of ROS1 rearrangement with clinicopathological characteristics
| Variable | ROS1-positive | ROS1-negative | P | ||
|---|---|---|---|---|---|
| N = 5 | % | N = 122 | % | ||
| Age, years | |||||
| Median | 53 | 62 | 0.114 | ||
| Range | 41–62 | 26–82 | |||
| Gender | |||||
| Male | 0 | 0.0 | 76 | 62.3 | 0.009 |
| Female | 5 | 100.0 | 46 | 37.7 | |
| Smoking status | |||||
| Non-smokers | 5 | 100.0 | 62 | 50.8 | 0.059 |
| Smokers | 0 | 0.0 | 60 | 49.2 | |
| Stage | |||||
| I-IIIA | 0 | 0.0 | 62 | 50.8 | 0.058 |
| IIIB-IV | 5 | 100.0 | 60 | 49.2 | |
| Histologic subtype | |||||
| Acinar | 5 | 100.0 | 70 | 57.4 | 0.078 |
| Non-acinar | 0 | 0.0 | 52 | 42.6 | |
ROS1, c-ros oncogene 1.