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. 2015 May 19;19(7):1504–1519. doi: 10.1111/jcmm.12601

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© 2015 The Authors. Journal of Cellular and Molecular Medicine published by John Wiley & Sons Ltd and Foundation for Cellular and Molecular Medicine.

This is an open access article under the terms of the Creative Commons Attribution License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.

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CD34 immunohistochemistry reveals reduced expression in the papillary dermis of a psoriatic plaque (A) compared to the papillary dermis of distant uninvolved skin (B) and treated skin (C). (A) The blood vessels are more numerous and dilated in the psoriatic plaque dermis compared to (B and C). Also, no CD34 positivity was found in interstitial cells in the papillary dermis. (B) In the papillary dermis of uninvolved skin, telocytes (TC; blue arrows) appear positive for CD34 in the vicinity of blood vessels. (C) The presence of CD34-positive telocytes (TC; blue arrows) was also noted in the papillary dermis of treated skin, with telopodes running parallel to the basement membrane of the epidermis. Black arrows indicate blood vessels. Magnification 400×.