Skip to main content
. 2015 Jun 8;19(7):1538–1547. doi: 10.1111/jcmm.12596

Figure 4.

Figure 4

IL-10 signalling proteins in the IL-10 receptors-blocked cells. E19 foetal alveolar type II cells were exposed to 65%-hyperoxia for 24 hrs. IL-10 signalling proteins were assessed by Western blot using phospho-specific antibodies after blocking IL-10 receptors with siRNA. Phosphorylated JAK1 (A) and TYK2 (B) were down-regulated, and phosphorylated STAT3 was enhanced in the hyperoxic cells blocked with IL-10 receptors siRNA, compared to the control cells. C and O mean control and 65%-oxygen, respectively, and OsiRNA and IL-10R-siRNA mean 65%-oxygen with IL-10 receptors’ siRNA and IL-10 receptors with siRNA, respectively. The results are represented as the mean ± SD from three different experiments.