Table II. Impact of Influenza Infection Upon Clinical Factors During Influenza-Related Encounters.
| Impact of influenza infection | Influenza-related clinical encounters (N = 27) | Severe influenza disease requiring respiratory support (N = 4)a |
|---|---|---|
| Duration of fever, mean days (range) | 4.6 (0–16) | 8.8 (3–16) |
| Duration of symptoms, mean days (range) | 11.1 (3–27) | 18.8 (14–21) |
| Duration of clinical encounter, median days (range) | 7.4 (0–44.9) | 24.2 (14.1–44.9) |
| Inpatient admission, n (%) | 18 (67) | 4 (100) |
| Maximum temperature, mean °C (range) | 39.2 (36.5–40.6) | 39.0 (38.2–40.1) |
| ANC, mean neutrophils/μl (range) | 2,269 (0–7,921) | 1,450 (64–2,772) |
| ANC<500/μl, n (%) | 8 (30) | 1 (25) |
| ALC<1,000/μl, n (%) | 17 (63) | 3 (75) |
| Oxygen requirement, n (%) | 6 (22) | 4 (100) |
| Mechanical ventilation, n (%) | 4 (15) | 4 (100) |
| BAL performed, n (%) | 4 (15) | 4 (100) |
| Chest radiograph change, n (%) | 9 (47)b | 4 (100) |
| Bacteremic, n (%) | 4 (15)c | 2 (50) |
| Antibiotic administered, n (%) | 19 (70) | 4 (100) |
| Antiviral administered, n (%) | 17 (63) | 4 (100) |
| Chemotherapy delayed, n (%) | 8 (40) | 4 (100) |
a
These four encounters with severe influenza disease are a subset of the total 27 encounters
b
Chest radiographs were obtained for 19 clinical encounters
c
Blood cultures were obtained for 24 clinical encounters.