. Author manuscript; available in PMC: 2016 Jul 1.

Published in final edited form as: Alzheimers Dement. 2015 Jul;11(7):815–822. doi: 10.1016/j.jalz.2015.05.010

Table 4.

Neuropathologic diagnosis of ADNI participants who came to autopsy as compared to clinical diagnosis.

Clinical diagnosis at expiration	ADNI: Neuropathologic Diagnosis [N (%)]												TOTAL (%) ^{^}
Clinical diagnosis at expiration	AD	AD +DLB	AD +TDP	AD +DLB+TDP	AD+DLB +TDP+AGD	AD +ALB+TDP	AD+AGD	AD+ALB	AD +HS+AGD	AD +TDP +Infarcts	AGD	Pending
DAT	14	10^*	1	1			1	2	2^†	1	1^**	2	35 (78)
DAT+DLB				1	1	1							3 (7)
Pending												7	7 (16)
TOTAL (%) ^{^}	14 (31)	10 (22)	1 (2)	2 (4)	1 (2)	1 (2)	1 (2)	2 (4)	2 (4)	1 (2)	1 (2)	9 (20)	45 (100)

AD, Alzheimer disease (NIA-AA score: A1, B0, C0 or greater); ALB, AD with amygdala Lewy bodies; DLB, dementia with Lewy bodies; AGD, argyrophilic grain disease; TDP, AD with TDP-43 proteinopathy in medial temporal lobe; HS, hippocampal sclerosis.

Note:

One case had additional AGD;

^†

One case had additional TDP-43 proteinopathy;

^**

One case had additional tangles in the medial temporal lobe;

^{^}

Figures are rounded and may not equal 100%. Small vessel disease (arteriolosclerosis and cerebral amyloid angiopathy) was a feature of all cases.