Table 3. Confocal-based LCS measurements—effects of perlecan deficiency.
Difference/%-(Hypo-WT)/WT |
||
---|---|---|
Measurement/Unit | Cortical | Cancellous |
Lacunar volume/μm3 | –17.6% P=0.11 | –23.6% P=0.02 |
Lacunar surface area/μm2 | –11.0% P=0.13 | –9.7% P=0.23 |
Lac. major axis/μm | –6.7% P=0.25 | –9.6% P=0.12 |
Lacunar density/μm–2 | –2.5% P=0.56 | –3.8% P=0.54 |
Canalicular No. | –15.7% P=0.001 | –11.9% P=0.03 |
Canalicular No. density/μm–2 | –9.1% P=0.03 | –5.0% P=0.22 |
Note: Comparisons were made between 32 weeks-old WT and perlecan deficient (Hypo) male mice.