Table 3.
Cancer Genetics task event types and their arguments.
| Type | Core arguments | Additional arguments |
|---|---|---|
| Anatomical | ||
| DEVELOPMENT | Theme (Anatomy) | |
| BLOOD VESSEL DEVELOPMENT | Theme?(Anatomy) | AtLoc? |
| GROWTH | Theme (Anatomy) | |
| DEATH | Theme (Anatomy) | |
| CELL DEATH | Theme?(Cell) | |
| BREAKDOWN | Theme (Anatomy) | |
| CELL PROLIFERATION | Theme (Cell) | |
| CELL DIVISION | Theme (Cell) | |
| CELL DIFFERENTIATION | Theme (Cell) | AtLoc? |
| REMODELING | Theme (Tissue) | |
| REPRODUCTION | Theme (Organism) | |
| Pathological | ||
| MUTATION | Theme (GGP) | AtLoc?, Site? |
| CARCINOGENESIS | Theme?(Anatomy) | AtLoc? |
| CELL TRANSFORMATION | Theme (Cell) | AtLoc? |
| METASTASIS | Theme?(Anatomy) | ToLoc |
| INFECTION | Theme?(Anatomy), Participant?(Organism) | |
| Molecular | ||
| METABOLISM | Theme (Molecule) | |
| SYNTHESIS | Theme (Simple chemical) | |
| CATABOLISM | Theme (Molecule) | |
| AMINO ACID CATABOLISM | Theme?(Molecule) | |
| GLYCOLYSIS | Theme?(Molecule) | |
| GENE EXPRESSION | Theme+(GGP) | |
| TRANSCRIPTION | Theme (GGP) | |
| TRANSLATION | Theme (GGP) | |
| PROTEIN PROCESSING | Theme (GGP) | |
| PHOSPHORYLATION | Theme (Molecule) | Site? |
| (other chemical modifications defined similarly to PHOSPHORYLATION) | ||
| PATHWAY | Participant (Molecule) | |
| General | ||
| BINDING | Theme+(Molecule) | Site? |
| DISSOCIATION | Theme (Molecule) | Site? |
| LOCALIZATION | Theme+(Molecule) | At/From/ToLoc? |
| Regulation | Theme (Any), Cause?(Any) | |
| POSITIVE REGULATION | Theme (Any), Cause?(Any) | |
| NEGATIVE REGULATION | Theme (Any), Cause?(Any) | |
| PLANNED PROCESS | Theme*(Any), Instrument*(Entity) | |
The indentation corresponds to ontological structure (is-a/part-of relations). The suffixes ?, *, and + denote zero or one, zero or more, and one or more arguments of the shown type (respectively). GGP stands for Gene or gene product. For brevity, additional argument types are not shown in table: the AtLoc, FromLoc and ToLoc arguments take an anatomical entity type, and Site arguments take a Protein domain or region or DNA domain or region entity type.