Table 2. Clinical response assessment according to RRM1 and ERCC1 expression.
Clinical response | L-RRM1 N = 41 (%) | H-RRM1 N = 12 (%) | P-values | L-ERCC1 N = 27 (%) | H-ERCC1 N = 26 (%) | P-values |
---|---|---|---|---|---|---|
CR+PR | 29 (70.7) | 3 (25.0) | 0.007 | 19 (70.4) | 13 (50.0) | 0.130 |
SD+PD | 12 (29.3) | 9 (75.0) | 8 (29.6) | 13 (50.0) |
Abbreviations: L-RRM1, low expression of RRM1; H-RRM1, high expression of RRM1; L-ERCC1, low expression of ERCC1; H-ERCC1, high expression of ERCC1; CR, complete remission; PR, partial remission; SD, stable disease; PD, progressive disease.