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. 2015 Jul 22;10(7):e0132437. doi: 10.1371/journal.pone.0132437

Fig 3. U2OS cell “fitness” is context-dependent.

Fig 3

(A) Aspect of U2OS G1, R1, and YFP co-cultures in fluorescence microscopy. Cells were plated at a 1:1 ratio as indicated (R1:G1 or R1:YFP) and allowed to grow for 1, 3 or 6 days. (B) Cp3-IF apoptosis quantification. R1 cells behave as “winners” in R1:YFP cultures but as “losers” in the presence of G1 cells, indicating that R1 cells assume “winner” or “loser” status depending on the properties of their co-culture partners. *: p<0.001 by Student’s t-test.