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. 2015 Jul 22;10(7):e0132166. doi: 10.1371/journal.pone.0132166

Table 3. Adjusted hazard ratios (95% CI) for incidence diabetes according to baseline smoking intensity 1 .

n Cases Incidence Age-adjusted incidence Attributable risk 2 Model 1 3 Model 2 4
Total 36756
Never smoker 19324 707 10.4 11.2 - 1.00 1.00
Current smoker (cigarettes smoked/d)
 1–10 3880 154 11.7 13.5 2.3 1.23 (1.03–1.46) 1.31 (1.10–1.58)
 11–20 11604 660 15.7 16.9 5.7 1.37 (1.22–1.53) 1.36 (1.22–1.52)
 21+ 1948 149 21.5 20.8 9.6 1.51 (1.26–1.81) 1.50 (1.25–1.80)
P for trend <0.001 <0.001
BMI <23 kg/m2 23432 617
Never smoker 10739 194 5.1 5.7 - 1.00 1.00
Current smoker (cigarettes smoked/d)
 1–10 2163 47 6.3 7.7 2.0 1.33 (0.96–1.84) 1.35 (0.98–1.87)
 11–20 5807 204 9.6 10.5 4.8 1.50 (1.22–1.85) 1.49 (1.21–1.83)
 21+ 851 42 13.7 12.4 6.7 1.74 (1.24–2.46) 1.74(1.23–2.45)
P for trend <0.001 <0.001
BMI ≥23 kg/m2 21971 1566
Never smoker 8585 513 17.0 17.8 - 1.00 1.00
Current smoker (cigarettes smoked/d)
 1–10 1717 107 18.9 20.9 3.1 1.26 (1.02–1.56) 1.28 (1.03–1.58)
 11–20 5797 456 21.8 23.9 6.1 1.28 (1.12–1.45) 1.28(1.12–1.45)
 21+ 1097 107 27.7 28.4 10.6 1.49 (1.20–1.84) 1.39 (1.12–1.72)
P for trend <0.001 <0.001
5 P for interaction 0.07

CI, confidence interval; BMI, body mass index.

1Analyses excluded former smoker (n = 8647).

2Difference in age-adjusted incidence rate per 1000 person-years between never smoker and current smoker.

3Adjusted for age (years), sex, and worksite.

4Adjusted for all factors in model 1 plus BMI (kg/m2), waist circumference (cm), and hypertension (yes or no).

5P for interaction for dichotomized variable of BMI (<23 or ≥23 kg/m2) on the association between smoking and type 2 diabetes was based on model 2 and was examined using the likelihood ratio test