Table 1.
Lowest Quartile | 2nd Quartile | 3rd Quartile | Highest Quartile | p-value | |
---|---|---|---|---|---|
HOMA-IR range | <0.72 | 0.72-1.52 | 1.521-2.81 | >2.81 | |
Sample size | 248 | 252 | 247 | 247 | |
Age, mean (SD) | 43.4 (9.0) | 45.2 (9.5) | 45.8 (9.4) | 45.9 (9.1) | 0.01 |
Years of Education, mean (SD) | 12.5 (3.1) | 12.8 (2.7) | 12.6 (2.8) | 11.9 (3.0) | 0.01 |
WRAT-R, mean (SD) | 91.9 (19.0) | 93.2 (15.8) | 92.5 (17.8) | 88.5 (18.7) | 0.02 |
Race, % | 0.16 | ||||
African-American, non-Hispanic | 66% | 67% | 70% | 62% | |
White, non-Hispanic | 12% | 13% | 8% | 9% | |
Hispanic | 20% | 16% | 18% | 26% | |
Other | 2% | 4% | 4% | 3% | |
HIV status, %HIV-uninfected | 22% | 24% | 26% | 28% | 0.003 |
CES-D ≥16, % | 28% | 23% | 28% | 35% | 0.03 |
Hepatitis C positive, % | 10% | 18% | 19% | 24% | 0.001 |
Metabolic Parameters | |||||
BMI, mean+SD | 25.9 (6.1) | 28.8 (6.8) | 31.2 (7.3) | 33.5 (9.4) | <0.001 |
Hypertension, % | 29% | 33% | 34% | 44% | 0.005 |
Smoking status, % | 0.80 | ||||
Never | 26% | 31% | 28% | 26% | |
Former | 47% | 41% | 42% | 43% | |
Recent | 27% | 28% | 30% | 31% | |
Fasting Chol. mg/dl, mean (SD) | 173.6 (32.8) | 178.5(38.3) | 180.7(39.9) | 179.4 (37.6) | 0.17 |
MAP, mean (SD) | 89.8 (13.4) | 91.0 (13.1) | 90.9 (12.4) | 91.4 (12.8) | 0.53 |
Waist-hip ratio | 0.87+0.07 | 0.89+0.07 | 0.91+0.07 | 0.93+0.07 | <0.001 |
Recent Alcohol use, % | 0.01 | ||||
Abstainer | 46% | 52% | 55% | 61% | |
Not heavy | 25% | 29% | 24% | 23% | |
Heavy | 29% | 19% | 21% | 16% | |
cART >95% compliance | 60% | 61% | 68% | 68% | |
CD4 count, % | 0.60 | ||||
>500 | 47% | 47% | 54% | 52% | |
200-500 | 36% | 41% | 31% | 35% | |
<200 | 16% | 12% | 15% | 13% | |
Plasma HIV RNA, % | 0.03 | ||||
Undetectable | 47% | 50% | 56% | 61% | |
<10,000 | 35% | 40% | 29% | 25% | |
≥10,000 | 18% | 10% | 15% | 14% |
Note. WRAT-R = Wide Range Achievement Test Scaled Score. “Recent” refers to within 6 months of the most recent WIHS visit. “Former” refers to any previous use, but not in the past 6 months.
CES-D = Center for Epidemiologic Studies Depression Scale; cART = combination antiretroviral therapy; MAP = mean arterial pressure.