Table 1.

Baseline demographic and clinical characteristics of the women by quartile of HOMA-IR

	Lowest Quartile	2nd Quartile	3rd Quartile	Highest Quartile	p-value
HOMA-IR range	<0.72	0.72-1.52	1.521-2.81	>2.81
Sample size	248	252	247	247
Age, mean (SD)	43.4 (9.0)	45.2 (9.5)	45.8 (9.4)	45.9 (9.1)	0.01
Years of Education, mean (SD)	12.5 (3.1)	12.8 (2.7)	12.6 (2.8)	11.9 (3.0)	0.01
WRAT-R, mean (SD)	91.9 (19.0)	93.2 (15.8)	92.5 (17.8)	88.5 (18.7)	0.02
Race, %					0.16
African-American, non-Hispanic	66%	67%	70%	62%
White, non-Hispanic	12%	13%	8%	9%
Hispanic	20%	16%	18%	26%
Other	2%	4%	4%	3%
HIV status, %HIV-uninfected	22%	24%	26%	28%	0.003
CES-D ≥16, %	28%	23%	28%	35%	0.03
Hepatitis C positive, %	10%	18%	19%	24%	0.001
Metabolic Parameters
BMI, mean+SD	25.9 (6.1)	28.8 (6.8)	31.2 (7.3)	33.5 (9.4)	<0.001
Hypertension, %	29%	33%	34%	44%	0.005
Smoking status, %					0.80
Never	26%	31%	28%	26%
Former	47%	41%	42%	43%
Recent	27%	28%	30%	31%
Fasting Chol. mg/dl, mean (SD)	173.6 (32.8)	178.5(38.3)	180.7(39.9)	179.4 (37.6)	0.17
MAP, mean (SD)	89.8 (13.4)	91.0 (13.1)	90.9 (12.4)	91.4 (12.8)	0.53
Waist-hip ratio	0.87+0.07	0.89+0.07	0.91+0.07	0.93+0.07	<0.001
Recent Alcohol use, %					0.01
Abstainer	46%	52%	55%	61%
Not heavy	25%	29%	24%	23%
Heavy	29%	19%	21%	16%
cART >95% compliance	60%	61%	68%	68%
CD4 count, %					0.60
>500	47%	47%	54%	52%
200-500	36%	41%	31%	35%
<200	16%	12%	15%	13%
Plasma HIV RNA, %					0.03
Undetectable	47%	50%	56%	61%
<10,000	35%	40%	29%	25%
≥10,000	18%	10%	15%	14%

Note. WRAT-R = Wide Range Achievement Test Scaled Score. “Recent” refers to within 6 months of the most recent WIHS visit. “Former” refers to any previous use, but not in the past 6 months.

CES-D = Center for Epidemiologic Studies Depression Scale; cART = combination antiretroviral therapy; MAP = mean arterial pressure.