Table 1. Susceptibility to antibiotics of S. maltophilia benzalkoniumbenzalkonium chloride resistant mutants, and their complemented derivatives.
MIC (mg/L) | Strains | |||||||||
---|---|---|---|---|---|---|---|---|---|---|
D457 (wt) | Bz4 | Bz6 | ||||||||
Plasmid | pVLT31 | pBS37 | pBS41 | pVLT31 | pBS42 | pVLT31 | pBS38 | |||
Amikacin | 8 | 4 | 3 | 4 | 8 | 6 | 8 | 16 | 16 | 16 |
Gentamicin | 2 | 2 | 2 | 2 | 2 | 2 | 2 | 2 | 3 | 3 |
Aztreonam | 24 | 12 | 16 | 12 | >256 | >256 | >256 | 128 | 48 | 48 |
Cefepime | 16 | 12 | 16 | 12 | 48 | 48 | 48 | 24 | 24 | 24 |
Ceftazidime | 0.38 | 0.25 | 0.5 | 0.38 | 1.5 | 1 | 1.5 | 1 | 1.5 | 1.5 |
Piperacillin | 64 | 48 | 64 | 48 | >256 | >256 | >256 | >256 | >256 | >256 |
Polymyxin B | 6 | 6 | 6 | 6 | 12 | 6 | 6 | 12 | 6 | 6 |
Chloramphenicol | 6 | 8 | 6 | 6 | 6 | 6 | 8 | 6 | 12 | 12 |
Gatifloxacin | 0.125 | 0.125 | 0.190 | 0.125 | 0.38 | 0.38 | 0.38 | 2 | 1.5 | 1.5 |
Levofloxacin | 0.38 | 0.25 | 0.38 | 0.25 | 0.5 | 0.5 | 0.5 | 2 | 1.5 | 1.5 |
Ofloxacin | 0.75 | 0.75 | 0.75 | 0.75 | 1.5 | 1.5 | 1.5 | 8 | 8 | 6 |
Ciprofloxacin | 1 | 1.5 | 1.5 | 1 | 2 | 2 | 2 | >32 | >32 | >32 |