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. 2015 Jul 22;11(7):e1005371. doi: 10.1371/journal.pgen.1005371

Table 3. Environmental and lifestyle indexes (ELIs) for the GWAS-studied diseases.

Disease N of publications containing: ELI
Disease Name (DN) DN AND "environment" DN AND "lifestyle"
Obesity 210416 7892 15834 112.8
Type 2 diabetes 113333 2180 6477 76.4
Major depressive disorder 96868 3626 3466 73.2
Asthma 147762 9239 1152 70.3
Atopic dermatitis 19705 1100 144 63.1
Autism 28552 1437 98 53.8
Attention deficit hyperactivity disorder 25208 1160 164 52.5
Melanoma 98871 4546 237 48.4
Schizophrenia 112478 4004 949 44.0
Bipolar disorder 38944 1016 524 39.5
Coronary heart disease 262453 4267 5647 37.8
Psoriasis 37149 1208 167 37.0
Type 1 diabetes 68482 1561 875 35.6
Alzheimer's disease (late onset) 2958 56 35 30.8
Multiple sclerosis 63493 1565 331 29.9
Age-related macular degeneration 21515 506 111 28.7
Migraine 29512 569 264 28.2
Sudden cardiac arrest 25821 487 229 27.7
Breast cancer 292315 4727 2742 25.6
Migraine with aura 4446 89 23 25.2
Amyotrophic lateral sclerosis 18004 394 49 24.6
Amyotrophic lateral sclerosis (sporadic) 18004 394 49 24.6
Inflammatory bowel disease 74179 1425 351 23.9
Prostate cancer 123622 1855 1040 23.4
Colorectal cancer 172036 2470 1356 22.2
Crohn's disease 41342 732 178 22.0
Ulcerative colitis 36344 600 168 21.1
Parkinson's disease 76837 1368 248 21.0
Lung cancer 245974 4112 916 20.4
Myopia (pathological) 3990 77 2 19.8
Chronic kidney disease 117185 1281 961 19.1
Endometriosis 21212 342 59 18.9
Bladder cancer 62487 884 289 18.8
Systemic sclerosis 22938 387 36 18.4
Systemic lupus erythematosus 58576 929 110 17.7
Rheumatoid arthritis 120346 1578 393 16.4
Testicular germ cell tumor 27123 313 99 15.2
Ovarian cancer 86537 888 353 14.3
Graves' disease 18020 196 45 13.4
Celiac disease 20718 213 55 12.9
Acute lymphoblastic leukemia 32530 335 57 12.1
Chronic lymphocytic leukemia 19285 209 23 12.0
Pancreatic cancer 73158 622 172 10.9
Primary biliary cirrhosis 12347 93 25 9.6