Skip to main content
. 2015 Jul 23;5:12379. doi: 10.1038/srep12379

Table 6. Effect of CdCl2(C14H21N3O 2) complex on AOM-induced colonic ACF containing four or more aberrant crypts in rats.

  No. of crypts per ACF
   
Treatment group 1 crypt 2 crypt 3 crypt 4 crypt and more Total ACF Inhibition %
Vehicle control group 0.0 ± 0.0 0.0 ± 0.0 0.0 ± 0.0 0.0 ± 0.0 0.0 ± 0.0 0.0 ± 0.0
Cancer control group 9 ± 0.43 27 ± 3.27 21 ± 3.27 30 ± 1.27 88 ± 6.7 0
Positive control group 2 ± 0.03* 6 ± 0.69* 5 ± 0.64* 10 ± 0.26* 22 ± 2.81* 75.2*
Low dosage of complex (25 mg/kg) 2 ± 0.71* 5 ± 0.14* 5 ± 0.19* 14 ± 1.04* 26 ± 2.70* 71.3*
High dosage of complex (50 mg/kg) 2 ± 0.41* 5 ± 0.52* 4 ± 0.27* 13 ± 1.13* 24 ± 1.53* 73.4*

Values are expressed as the means ± S.E.M. Significance was set at P < 0.05, compared with cancer control group.