Table 7. Effect of CdCl2(C14H21N3O2 ) complex on regional distribution of colonic ACF in AOM-induced colonic cancer in rats.
ACF Counting |
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Groups | Proximal | Middle | Distal | Total |
Vehicle control group | 0.0 ± 0.0 | 0.0 ± 0.0 | 0.0 ± 0.0 | 0.0 ± 0.0 |
Cancer control group | 25 ± 3.66 | 43 ± 5.77 | 11 ± 3.79 | 88 ± 6.7 |
Positive control group | 1 ± 0.0* | 18 ± 2.37* | 2 ± 0.0* | 22 ± 2.81* |
Low dosage of complex (25 mg/kg) | 8 ± 1.04* | 15 ± 7.89* | 3 ± 0.5* | 26 ± 2.70* |
High dosage of complex (50 mg/kg) | 1 ± 0.02* | 20 ± 4.84* | 3 ± 0.3* | 24 ± 1.53* |
Values are expressed as the means ± S.E.M. Significance was set at P < 0.05, compared with cancer control group.