Figure 3.
Effect of lactose-functionalized dendrimers on galectin-3-induced homotypic aggregates of DU-145 (yellow bars) and HT-1080 cells (blue bars): * statistical significance with respect untreated cells, ● statistical significance with respect to the galectin-3 standard. One symbol represents p < 0.05, two symbols represent p < 0.01, and three symbols represent p < 0.001. No dendrimer was added to the “Untreated Cells” or to the “0” entries on the x-axis. A) Dendrimer 1 inhibits aggregation in both cell lines. B) Dendrimer 2 inhibits aggregation slightly by DU-145 cells, but has little effect on HT-1080 cells.