Table 1.

Identification of differentially expressed proteins in plasma in dairy cows with laminitis by MALDI TOF MS/MS

NO. spot		Change	Protein name	NCBI accession	pI;	Mw	Coverage	Score	NO. of peptides identified
1	773	UP	3-hydroxy-3-methylglutaryl-Coenzyme A reductase(HMGCR)	gi|157785597	6.27;	99155	33 %	184	16
2	777	UP	SPEG complex locus	gi|215599780	8.83;	357571	6 %	73	15
3	889	UP	Serum albumin	gi|76445989	6.09;	55487	18 %	78	6
4	1297	UP	Complement component C9;	gi|85718632	5.66;	63327	20 %	108	9
5	1468	UP	serum albumin	gi|76445989	6.09;	55487;	18 %	73	5
6	1477	UP	serum albumin	gi|76445989	6.09;	55487	27 %	78	8
7	1503	UP	Haptoglobin, HPT	gi|94966763	7.83;	45629	47 %	136	9
8	1534	UP	Isocitrate Dehydrogenase 1, IDH1	gi|89573995	6.12;	41658	49 %	175	10
9	1682	UP	60S ribosomal protein L5, RPL5	gi|78369655	9.73;	34551	28 %	63	7
10	1915	UP	Conglutinin, CONG_BOVIN	gi|395268	5.82;	38370	27 %	73	4
11	2025	UP	Apolipoprotein A-IV precursor	gi|296480272	5.30;	42963	20 %	92	7
12	2045	UP	Zinc finger protein 300-like, ZNF300	gi|297493133	8.66;	27753	59 %	181	6
13	2049	UP	Transmembrane protein, TMP10	gi59858239	6.85;	15875	59 %	199	3
14	2329	UP	Apolipoprotein A-IV precursor, apoA-IV	gi|296480272	5.30;	42963	55 %	174	5
15	2340	UP	Apolipoprotein A-I, apoA-I, apoA-I	gi|245563	5.57;	28415	67 %	242	7
16	808	Down	Ectoderm-neural cortex protein 1, ENC1	gi|118151210	6.40;	67257	46 %	176	15
17	1615	Down	Glycerol-3-phosphate dehydrogenase 1-like protein, GPD1L	gi|154152135	6.13;	38841	42 %	133	10
18	1933	Down	complement component 4 binding protein, alpha chain-like, C4BP	gi|76677514	6.34;	22393	42 %	123	6
19	1949	Down	complement component C9 precursor	gi|78369352	5.66;	63327	18 %	101	7