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. 2015 Jul 23;5:12363. doi: 10.1038/srep12363

Figure 2. Effect of Rap2B on cell proliferation of breast cancer cells.

Figure 2

(A) CCK-8 cell proliferation assay after Rap2B knockdown in Bcap-37 and MDA-MB-231 cells. (B) CCK-8 cell proliferation assay after Rap2B overexpressed in breast cancer cells. (C) Influence of Rap2B gene silencing on the cell cycle of breast cancer cells. The percentage of G1 population cells was measured by flow cytometry after Rap2B knockdown in breast cancer cells. (D) Influence of Rap2B gene overexpression on cell cycle analysis of breast cancer cells. The percentage of cells at G1 stage was calculated using ModFit LT 3.0 software. All experiments were carried out in triplicate. Data are presented as mean ± SD (n = 3). *P < 0.05, **P < 0.01 in comparison with respective group.