Table 1B.
Base line comparison of AKI urinary biomarkers in mdx23 and wild type C57BL10 mice (mean ± SD).
| Strain | Albumin (μg/ml) | KIM1 (pg/ml) | Cystatin C (μg/ml) | Clusterin (μg/ml) | EGF (μg/ml) | NGAL (ng/ml) | GGT1 (ng/ml) | OPN (μg/ml) |
|---|---|---|---|---|---|---|---|---|
| C57BL10 (n = 12) | 36.34 ± 9.74 | 74.45 ± 2.86 | 0.10 ± 0.02 | 0.84 ± 0.27 | 0.81 ± 0.20 | 1.23 ± 0.58 | 11.30 ± 0.91 | 1.22 ± 0.33 |
| mdx23 (n = 12) | 75.97 ± 21.52 | 72.44 ± 4.99 | 0.13 ± 0.03 | 0.72 ± 0.17 | 0.48 ± 0.03 | 4.21 ± 0.73 | 11.69 ± 3.67 | 1.06 ± 0.29 |
| Folds (mdx23/C57BL10) | 2.09 | 0.97 | 1.3 | 0.86 | 0.51 | 3.42 | 1.03 | 0.87 |
| P value | <0.0001 | >0.05 | 0.0175 | >0.05 | <0.001 | <0.0001 | >0.05 | >0.05 |
Abbreviations: AKI, acute kidney injury; KIM1, kidney injury molecule-1; EGF, pro-epidermal growth factor; NGAL, neutrophil gelatinase-associated lipocalin; GGT1, gamma-glutamyltranspeptidase 1; OPN, osteopontin. P values < 0.05 are significant.