Table 1C.
Creatinine normalization of base line comparison of AKI urinary biomarkers in mdx23 and wild type C57BL10 mice (mean ± SD).
| Strain | Albumin (μg/mg) | KIM1 (ng/mg) | Cystatin C (μg/mg) | Clusterin (μg/mg) | EGF (μg/mg) | NGAL (ng/mg) | GGT1 (ng/mg) | OPN (μg/ml) |
|---|---|---|---|---|---|---|---|---|
| C57BL10 (n = 12) | 98.19 ± 21.50 | 0.20 ± 0.03 | 0.28 ± 0.04 | 2.26 ± 0.63 | 2.17 ± 0.37 | 69.21 ± 31.31 | 31.20 ± 14.97 | 3.29 ± 0.71 |
| mdx23 (n = 12) | 384.22 ± 98.85 | 0.33 ± 0.03 | 0.60 ± 0.05 | 3.30 ± 0.64 | 2.17 ± 0.32 | 384.0 ± 58.05 | 53.82 ± 19.60 | 4.81 ± 1.01 |
| Folds (mdx23/C57BL10) | 3.91 | 1.65 | 2.14 | 1.46 | 1 | 5.55 | 1.72 | 1.46 |
| P value | <0.0001 | <0.0001 | <0.0001 | 0.0006 | >0.05 | <0.0001 | 0.0044 | 0.0003 |
Abbreviations: AKI, acute kidney injury; KIM1, kidney injury molecule-1; EGF, pro-epidermal growth factor; NGAL, neutrophil gelatinase-associated lipocalin; GGT1, gamma-glutamyltranspeptidase 1; OPN, osteopontin. P values < 0.05 are significant.