TABLE 5.
HRs for CP and exposures to vaginal infection, fever, and smoking by Apgar score
| Factors | Apgar <10
|
Apgar = 10
|
||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Number
|
Crude HR | aHRa | 95% CI | Number
|
Crude HR | aHRa | 95% CI | |||||||
| Non-CP
|
CP
|
Non-CP
|
CP
|
|||||||||||
| Unexposed | Exposed | Unexposed | Exposed | Unexposed | Exposed | Unexposed | Exposed | |||||||
| Vaginal infections (all) | 4486 | 1236 | 31 | 13 | 1.52 | 1.54 | (0.79–2.99) | 57,693 | 15,298 | 61 | 23 | 1.42 | 1.45 | (0.77–2.71) |
|
| ||||||||||||||
| Untreated | 5181 | 541 | 36 | 8 | 2.13 | 2.11 | (0.97–4.61) | 66,007 | 6984 | 75 | 9 | 1.22 | 1.24 | (0.58–2.67) |
|
| ||||||||||||||
| Treated | 5027 | 695 | 39 | 5 | 1.04 | 1.08 | (0.44–2.61) | 64,677 | 8314 | 70 | 14 | 1.59 | 1.62 | (0.79–3.32) |
|
| ||||||||||||||
| Fever | 4065 | 1635 | 30 | 13 | 1.08 | 1.16 | (0.53–2.50) | 51,873 | 20,761 | 49 | 35 | 1.78 | 1.74 | (1.04–2.91) |
|
| ||||||||||||||
| Smoking (all) | 4257 | 1526 | 37 | 7 | 0.53 | 0.55 | (0.24–1.25) | 54,443 | 19,367 | 56 | 28 | 1.40 | 1.45 | (0.91–2.30) |
|
| ||||||||||||||
| 1–9 cigarettes/d | 4998 | 785 | 42 | 2 | 0.30 | 0.29 | (0.06–1.31) | 63,926 | 9884 | 74 | 10 | 0.98 | 1.01 | (0.41–2.46) |
|
| ||||||||||||||
| ≥10 cigarettes/d | 5041 | 742 | 39 | 5 | 0.78 | 0.87 | (0.35–2.16) | 64,327 | 9483 | 66 | 18 | 1.84 | 1.94 | (1.18–3.17) |
aHR, adjusted hazard ratio; CI, confidence interval; CP, cerebral palsy; HR, hazard ratio.
a
All adjusted for maternal age (younger than 35, 35–39, 40–44, 45 years old or older), alcohol drink per week (never, 1 or fewer, 2–4, 5 or more), binge drinking, combined socioeconomic status group (1, 2, 3), season of birth (fall, winter, spring, summer), number per household (1, 2, 3, 4 or more), birth year (before 2000, 2000 or later), and smoking (0, 1–9, 10) except in analysis in which smoking is an exposure.
Streja. Cerebral palsy, smoking, and maternal infections. Am J Obstet Gynecol 2013.