TABLE 6.
HRs for sCP and exposures to vaginal infection, fever, and smoking by Apgar score
| Factors | Apgar <10
|
Apgar = 10
|
||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Number
|
Crude HR | aHRa | 95% CI | Number
|
Crude HR | aHRa | 95% CI | |||||||
| Non-CP
|
CP
|
Non-CP
|
CP
|
|||||||||||
| Unexposed | Exposed | Unexposed | Exposed | Unexposed | Exposed | Unexposed | Exposed | |||||||
| Vaginal infections (all) | 4486 | 1236 | 23 | 13 | 2.05 | 2.07 | (1.03–4.13) | 57,693 | 15,298 | 53 | 21 | 1.49 | 1.51 | (0.81–2.81) |
|
| ||||||||||||||
| Untreated | 5181 | 541 | 28 | 8 | 2.87 | 2.80 | (1.23–6.33) | 66,007 | 6984 | 65 | 9 | 1.4 | 1.42 | (0.67–3.04) |
|
| ||||||||||||||
| Treated | 5027 | 695 | 31 | 5 | 1.40 | 1.46 | (0.59–3.59) | 64,677 | 8314 | 62 | 12 | 1.57 | 1.59 | (0.77–3.28) |
|
| ||||||||||||||
| Fever | 4065 | 1635 | 26 | 9 | 0.86 | 0.94 | (0.42–2.09) | 51,873 | 20,761 | 47 | 27 | 1.43 | 1.36 | (0.81–2.27) |
|
| ||||||||||||||
| Smoking (all) | 4257 | 1526 | 30 | 6 | 0.56 | 0.56 | (0.23–1.34) | 54,443 | 19,367 | 47 | 27 | 1.61 | 1.68 | (0.99–2.86) |
|
| ||||||||||||||
| 1–9 cigarettes/day | 4998 | 785 | 35 | 1 | 0.18 | 0.18 | (0.02–1.36) | 63,926 | 9884 | 64 | 10 | 1.17 | 1.22 | (0.47–3.16) |
|
| ||||||||||||||
| ≥10 cigarettes/day | 5041 | 742 | 31 | 5 | 0.96 | 1.03 | (0.40–2.61) | 64,327 | 9483 | 57 | 17 | 2.21 | 2.21 | (1.33–3.67) |
aHR, adjusted hazard ratio; CI, confidence interval; CP, cerebral palsy; HR, hazard ratio.
a
All adjusted for maternal age (younger than 35, 35–39, 40–44, 45 years old or older), alcohol drink per week (never, 1 or fewer, 2–4, 5 or more), binge drinking, combined socioeconomic status group (1, 2, 3), season of birth (fall, winter, spring, summer), number per household (1, 2, 3, 4 or more), birth year (before 2000, 2000 or later), and smoking (0, 1–9, 10) except in analysis in which smoking is an exposure.
Streja. Cerebral palsy, smoking, and maternal infections. Am J Obstet Gynecol 2013.