Table 1.

Primary (metabolic) and secondary (regulatory) functions currently recognized for the PTS.

Primary Metabolic Functions

Catalysis of:

Sugar transport

Sugar phosphorylation

Sugar chemoreception

Secondary Regulatory Functions

Control of the activities of:

PTS permeases

Non-PTS permeases

Catabolic enzymes

Adenylate cyclase

Transcription factors (many)

Control of physiological processes including:

Ionic homeostasis (potassium transport)

Glycogen accumulation

Polyhydroxybutyrate storage

Nitrogen utilization

Phosphorous metabolism

Biofilm formation

Virulence

Transposon-mediated directed mutation