Skip to main content
. 2015 May 11;200(3):737–754. doi: 10.1534/genetics.115.177303

Table 1. Summary of rates of tract length change calculated from liquid, colony, and microcolony time courses.

Genotype Rates of tract length changes
Liquida (95% C.I.)b Colony (95% C.I.) Microcolony (95% C.I)
MSH3(CTG) 1.2 × 10−3 (9.0 × 10−4 to 1.6 × 10−3) 1.5 × 10−2 (1.2 × 10−2 to 1.9 × 10−2) 3.5 × 10−2 (2.8 × 10−2 to 4.2 × 10−2)e
MSH3(CAG) 3.1 × 10−3 (2.4 × 10−3 to 3.4 × 10−3) NDc ND
msh3Δ(CTG) 3.1 × 10−4 (1.3 × 10−4 to 6.0 × 10−4) 3.6 × 10−3 (1.5 × 10−3 to 7.2 × 10−3)d 1.6 × 10−2 (1.1 × 10−2 to 2.2 × 10−2)f
msh3Δ(CAG) 1.3 × 10−4 (2.9 × 10−4 to 3.7 × 10−4) ND ND
MSH3(CTG)25 <5 × 10−5g,h ND <1.2 × 10−3g,h
MSH3(CAG)25 5.1 × 10−5h ND ND
a

Expansions only.

b

95% C.I.s determined by F-statistic.

c

Not determined.

d

Predominantly contractions.

e

Slight bias toward expansions.

f

Bias toward contractions.

g

No tract changes observed.

h

Low numbers precluded accurate calculation of 95% C.I.