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. Author manuscript; available in PMC: 2015 Jul 23.
Published in final edited form as: Nat Chem. 2013 Mar 31;5(5):423–427. doi: 10.1038/nchem.1612

Figure 3. Mechanism and scope of Au-catalyzed benzannulation of siloxy alkyne with 2-pyrones.

Figure 3

Siloxy alkyne 6 undergoes a [4+2] cycloaddition with 2-pyrone 7 to give a putative intermediate A, which undergoes subsequent fragmentation to deliver carboxylic acid 9. Compound numbers are shown in bold. Isolated yields are shown below each compound number. R is a generic alkyl or aryl substituent.