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. 2015 Jul 23;9(7):e0003841. doi: 10.1371/journal.pntd.0003841

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© 2015 Simpson et al

This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are properly credited.

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Fig 11 — A mapped gRNA peak from mc71 encoding the gND9X gRNA is expanded to the nucleotide level to illustrate the characteristic 5’ flush edge and 3’ heterogeneity. Note that the major 5' start site is located 3 nt upstream of the 5' end of the identified gRNA/edited mRNA duplex. See Fig 10 legend for details.