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. 2015 Jul 23;10(7):e0133880. doi: 10.1371/journal.pone.0133880

Fig 2. Morphology of pericytes covering the abluminal surface of the blood vessel and their effect on PECAM-1 expression.

Fig 2

(A) The confocal micrograph shows that pericytes are evenly distributed on the blood vessel network while covering the vessel. (B) Intact covering of the vessel with pericyte processes, as well as lumen formation of the blood vessel, can be observed based on the enlarged image of the white dotted box in (A). (C, D) PECAM-1 expression is broken occasionally in EC-only blood vessels (C) compared with continuous expression in pericyte-covered vessels. Microvascular networks were stained with anti-CD31 (red), the nucleus with Hoechst 33342 (blue), and pericytes with α-SMA (green). Scale bars, 100 μm (A, C, D) or 50 μm (B)